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International Journal of Mass Spectrometry

PTR-MS studies of the reactions of H<sub>3</sub>O<sup>+</sup> with a number of deuterated volatile organic compounds and the subsequent sequential reactions of the primary product ions with water under normal and humid drift tube conditions: Implications for use of deuterated compounds for breath analysis
Decomposition of overlapped ion mobility peaks by sparse representation
Helmut Schwarz honor issue: Curriculum vitae
Role of water in molecular oxygen activation in hydrated chromium(I) cluster ions: A theoretical insight
Structural characterization of synthetic peptides using electrospray ion mobility spectrometry and molecular dynamics simulations

European Journal of Mass Spectrometry

Journal of Mass Spectrometry

Imaging mass spectrometry of gold nanoparticles in a tissue section as an immunohistochemical staining mass probe
For analysis of low abundance peptides in a tissue section, immunohistochemical staining through antibody‐antigen interaction is a usual technique. The antibody is conjugated with a probe moiety that aids in highly sensitive detection. Gold nanoparticles, which show excellent chemical stability and variation of surface modifications, are expected to act as a sensitive mass probe to […]
Isolation and characterization of kurstakin and surfactin isoforms produced by Enterobacter cloacae C3 strain
In this work, the extraction, structural analysis, and identification as well as antimicrobial, anti‐adhesive, and antibiofilm activities of lipopeptides produced by Enterobacter cloacae C3 strain were studied. A combination of chromatographic and spectroscopic techniques offers opportunities for a better characterization of the biosurfactant structure. Thin layer chromatography (TLC) and HPLC for amino acid composition determination […]
Ultrasonication‐assisted spray ionization‐based micro‐reactors for online monitoring of fast chemical reactions by mass spectrometry
Microfluidics can be used to handle relatively small volumes of samples and to conduct reactions in microliter‐sized volumes. Electrospray ionization can couple microfluidics with mass spectrometry (MS) to monitor chemical reactions online. However, fabricating microfluidic chips is time‐consuming. We herein propose the use of a micro‐reactor that is sustained by two capillaries and an ultrasonicator. […]
Top‐down analysis of novel synthetic branched proteins
A strategy for top‐down analysis of branched proteins has been reported earlier, which relies on electron transfer dissociation assisted by collisional activation, and software designed for graphic interpretation of tandem mass spectra and adapted for branched proteins. In the present study, the strategy is applied to identify unknown and novel products of reactions in which […]
A high‐throughput glutathione trapping assay with combined high sensitivity and specificity in high resolution mass spectrometry by applying product ion extraction and data‐dependent neutral loss
Reactive metabolites are thought to play a pivotal role in the pathogenesis of some drug induced liver injury (DILI) and idiosyncratic adverse drug reactions (IADRs), which is of concern to patient safety and has been a cause of drugs being withdrawn from the market place. To identify drugs with a lower propensity for causing DILI […]

Journal of the American Society for Mass Spectrometry

High-Resolution Mass Spectrometry Quantification: Impact of Differences in Data Processing of Centroid and Continuum Data December 17, 2018
Use of a Continuous Stirred Tank Reactor for the Determination of Electrospray Response Factors and Its Application to Underivatized Sugars Under Various Solvent Parameters December 17, 2018
Editorial and Review: 33 rd Asilomar Conference on Mass Spectrometry—Impact of Metabolomics in Translational and Clinical Research December 14, 2018
A Method for Defining the Position of Ion Formation in a MALDI TOFMS by Analysis of the Laser Image on the Sample Surface December 14, 2018
Development of Novel Free Radical Initiated Peptide Sequencing Reagent: Application to Identification and Characterization of Peptides by Mass Spectrometry December 13, 2018

Mass Spectrometry Reviews

Rapid Communications in Mass Spectrometry

Investigation of the chemical structure and formation mechanism of polydopamine from self‐assembly of dopamine by liquid chromatography and mass spectrometry coupled with isotope‐labelling techniques
RATIONALE Dopamine (Dp) is one of the neurotransmitters released by the brain, and it was recently observed to undergo “self‐polymerization” to form polydopamine (polyDp) functional materials, with poorly‐understood the polymerization mechanism. In this study, we investigated the chemical structure of polyDp as well as the mechanism of its formation using a combination of mass spectrometric […]
Sensitive detection of topiramate degradation products by high‐performance liquid chromatography/electrospray ionization mass spectrometry using ion‐pairing reagents and polarity switching
Rationale The chromatographic analysis of topiramate and its degradation products is challenging due to the absence of chromophoric moieties in their structures, the wide polarity range of the compounds and their ionization differences. This work proposes two new mass spectrometry approaches for evaluating these analytes. Methods Based on the calculated experimental limit of detection (LOD), […]
Compositional and beam‐size‐dependent effects on pressure baseline in clumped isotope mass spectrometry
Rationale The analysis of carbonate samples for the application of clumped isotopes to paleoclimate reconstruction necessitates smaller beam intensities. However, there is a relationship between beam intensity and pressure‐dependent baseline (PBL), and therefore between beam intensity and the correction for PBL. Here we explain the relationship between PBL and beam intensity to develop a better […]
Investigations into the Performance of Travelling Wave‐Enabled Conventional and Cyclic Ion Mobility Systems to Characterise Protomers of Fluoroquinolone Antibiotic Residues
Fluoroquinolones (FLQs) are a class of antimicrobial agents which have been administered to livestock for infection prevention/control and growth promotion. In this work blank porcine muscle extract (fortified with FLQs) has been screened for the FLQ protomer species (resulting from different sites of protonation) using the cumulative specificity of Ultra High Performance Liquid Chromatography coupled […]
Gold‐Nanoparticle‐Coated Magnetic Beads for Concentration and Ionization of Analytes for Laser Desorption/Ionization Mass Spectrometry
Rationale Magnetic particles coated with Au NPs (Au‐MAGs) were developed and used (1) for sample concentration and (2) as a solid matrix for laser adsorption/desorption (LDI)‐mass spectrometry. Methods The Au‐MAGs were prepared by (1) coating polystyrene on iron oxide NPs (PS‐MNPs), (2) coating poly‐l‐lysine on the PS‐MNPs (PLL‐coated PS‐MNPs), and (3) coating negatively charged Au […]

Cyclotrons

The Cyclotron: Crafting an Early Tech Marvel from the Life Magazine archives in 1948.

Posted on May 3, 2012Author kkmurrayCategories Education, Misc

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