Charge site derivatization

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K. K. Murray, R. K. Boyd, M. N. Eberlin, G. J. Langley, L. Li and Y. Naito, Pure Appl. Chem., 2013, 85, 1515-1609, 10.1351/PAC-REC-06-04-06.

Charge site derivatization
Chemical derivatization of molecules to introduce a fixed charge site, thus improving ionization efficiency by electrospray ionization or matrix-assisted laser desorption/ionization and directing subsequent ion fragmentation in a manner that facilitates structure identification.

Note: Examples are quaternary ammonium or phosphonium derivatization.
Related Term(s):

X. Czeszak, W. Morelle, G. Ricart, D. Tétaert, J. Lemoine. Anal. Chem. 76, 4320 (2004). ( )

Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.

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