Isotope-coded affinity tag
From MS Terms
IUPAC RECOMMENDATIONS 2013 |
Isotope-coded affinity tag (ICAT) |
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Chemical labeling reagents used for relative quantitation in proteomics, consisting of a reactive group capable of labeling a defined amino acid side-chain, an isotopically coded linker, and a tag for the affinity isolation of labeled proteins and peptides. |
Related Term(s): |
Reference(s):
S. P. Gygi, B. Rist, S. A. Gerber, F. Turecek, M. H. Gelb, R. Aebersold. Nat. Biotech. 17, 994 (1999). (http://dx.doi.org/10.1038/13690 ) |
From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013. |