Lock mass

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IUPAC RECOMMENDATIONS 2013
Lock mass
Mass of an ion of known m/z value, derived from a suitable standard compound introduced into an ion source together with the sample to be analyzed, which permits real-time recalibration by correction of m/z shifts arising from instrumental drift.
Related Term(s):
Reference(s):

J. V. Olsen, L. M. F. de Godoy, G. Li, B. Macek, P. Mortensen, R. Pesch, A. Makarov, O. Lange, S. Horning, M. Mann. Mol. Cell Proteomics 4, 2010 (2005).

From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.

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