Sensitivity

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IUPAC RECOMMENDATIONS 2013

K. K. Murray, R. K. Boyd, M. N. Eberlin, G. J. Langley, L. Li and Y. Naito, Pure Appl. Chem., 2013, 85, 1515-1609, 10.1351/PAC-REC-06-04-06.

Sensitivity , A
Slope of the calibration curve.
Note 1: If the curve is not a straight line, sensitivity will be a function of analyte concentration or amount.
Note 2: If sensitivity is to be a unique performance characteristic, it must depend only on the chemical measurement process, not upon scale factors.
Related Term(s):
Reference(s):

IUPAC. Analytical Division. Compendium of Analytical Nomenclature (the “Orange Book”). Definitive Rules, 1979. Compiled by J. Inczédy, T. Lengyel, A. M. Ure. Blackwell Scientific Publications, Oxford (1997). On-line corrected version: http://www.iupac.org /publications/analytical compendium (2000).

IUPAC. Compendium of Chemical Terminology, 2nd ed. (the “Gold Book”). Compiled by A. D. McNaught and A.Wilkinson. Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic, J. Jirat, B. Kosata; updates compiled by A. Jenkins.

Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.


Index of Terms

 




Orange Book

ORANGE BOOK DEFINITION

IUPAC. Analytical Division. Compendium of Analytical Nomenclature (the “Orange Book”). Definitive Rules, 1979.

Sensitivity

This is the observed change in ion curent per unit mass of sample flow through the ion Source and is measured in coulomb per microgram, C μg-1. An alternative measure of sensitivity, more suitable for gases, is the observed change in partial pressure of the sample in the ion Source, expressed in ampere per pascal, A/Pa.

See also Orange Book Chapter} 18.4.3.2.

IUPAC Orange Book Chapter 12
Index of Orange Book Terms


Gold Book

GOLD BOOK DEFINITION

IUPAC. Compendium of Chemical Terminology, 2nd ed. (the “Gold Book”). Compiled by A. D. McNaught and A.Wilkinson. Blackwell Scientific Publications, Oxford (1997).

Sensitivity

sensitivity in mass spectrometry

http://goldbook.iupac.org/S05605.html

Two different measures of sensitivity are recommended. The first, which is suitable for relatively involatile materials as well as gases, depends upon the observed change in ion current for a particular amount or change of flow rate of sample though the ion source. A second method of stating sensitivity, that is most suitable for gases, depends upon the change of ion current related to the change of partial pressure of the sample in the ion source.

It is important that the relevant experimental conditions corresponding to sensitivity measurement should always be stated. These include in a typical case details of the instrument type, bombarding electron current, slit dimensions, angular collimation, gain of the multiplier detector, scan speed and whether the measured signal corresponds to a single mass peak or to the ion beam integrated over all masses. Some indication of the time involved in the determination should be given, e.g. counting time or band width. The sensitivity should be differentiated from the detection limit.

Source:

PAC, 1991, 63, 1541 (Recommendations for nomenclature and symbolism for mass spectroscopy (including an appendix of terms used in vacuum technology). (Recommendations 1991)) on page 1553

Orange Book, p. 206

IUPAC Gold Book
Index of Gold Book Terms