Category:Reaction monitoring: Difference between revisions

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===IUPAC reaction monitoring terms===
:{| class="wikitable"  border="1" style="border-collapse:collapse;" style="border-spacing: 1px; border: 5px solid purple;"
|-
! Term
!Acronym
! Definition
! Diagram
! Reference
|-
|[[Selected ion monitoring]]
|[[SIM]]
|Operation of a [[mass spectrometer]] in which the abundances of [[ion]]s of one or more specific ''[[m/z]]'' values are recorded rather than the entire [[mass spectrum]].
|&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<big><big> </big></big>
|[[Gold Book]]
|-
| [[Selected reaction monitoring]]
|[[SRM]]
| Data acquired from one or more specific product [[ion]]s corresponding to [[m/z]] selected [[precursor ion]]s recorded via two or more stages of [[mass spectrometry]].
:''Note 1'': Selected reaction monitoring in [[multiple-stage mass spectrometry]] is known as [[consecutive reaction monitoring]].
:''Note 2'': Selected reaction monitoring applied to multiple product ions from one or more [[precursor ion]]s is known as multiple reaction monitoring.
|[[File:SRM.jpg|center|20 px]]
|de Hoffmann. J. Mass Spectrom. 31, 129 (1996).
|-
| [[Consecutive reaction monitoring]]
|[[CRM]]
| [[Multiple-stage mass spectrometry]] experiment with three or more stages of [[m/z]] separation in which products of sequential fragmentation or bimolecular reactions are selected for detection.
|[[File:CRM.jpg|center|20 px]]
|Tomer, Guenat, Deterding. Anal. Chem. 60, 2232 (1988).
|-
|[[Multiple reaction monitoring]]
|[[MRM]]
|Application of [[selected reaction monitoring]] to multiple [[product ion]]s from one or more [[precursor ion]]s.
:Note: This term should not be confused with [[consecutive reaction monitoring]], which involves the serial application of three or more stages of selected reaction monitoring.
|[[File:MRM-Single.jpg|center|30 px]]
|Roepstorff, Fohlman. Biomed. Mass Spectrom. 11, 601 (1984).
|}
[[Category:Reactions]]
[[Category:Reactions]]
[[Category:Fragmentation]]

Latest revision as of 15:39, 10 June 2021

IUPAC reaction monitoring terms

Term Acronym Definition Diagram Reference
Selected ion monitoring SIM Operation of a mass spectrometer in which the abundances of ions of one or more specific m/z values are recorded rather than the entire mass spectrum.       Gold Book
Selected reaction monitoring SRM Data acquired from one or more specific product ions corresponding to m/z selected precursor ions recorded via two or more stages of mass spectrometry.
Note 1: Selected reaction monitoring in multiple-stage mass spectrometry is known as consecutive reaction monitoring.
Note 2: Selected reaction monitoring applied to multiple product ions from one or more precursor ions is known as multiple reaction monitoring.
SRM.jpg
de Hoffmann. J. Mass Spectrom. 31, 129 (1996).
Consecutive reaction monitoring CRM Multiple-stage mass spectrometry experiment with three or more stages of m/z separation in which products of sequential fragmentation or bimolecular reactions are selected for detection.
CRM.jpg
Tomer, Guenat, Deterding. Anal. Chem. 60, 2232 (1988).
Multiple reaction monitoring MRM Application of selected reaction monitoring to multiple product ions from one or more precursor ions.
Note: This term should not be confused with consecutive reaction monitoring, which involves the serial application of three or more stages of selected reaction monitoring.
MRM-Single.jpg
Roepstorff, Fohlman. Biomed. Mass Spectrom. 11, 601 (1984).