Peptide mass fingerprinting

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Peptide mass fingerprinting (PMF)
peptide mass fingerprinting

mass mapping

Method for protein analysis where an unknown protein is chemically or enzymatically cleaved into peptide fragments whose masses are determined by mass spectrometry. The peptide masses are compared to peptide masses calculated for known proteins in a database and analyzed statistically to determine the best match.

Related Term(s): accurate mass tag

D. J. C. Pappin, P. Hojrup, A. J. Bleasby. Curr. Biol. 3, 327 (1993). ( )

From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.

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