Difference between revisions of "Resolution (mass spectrometry)"

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Smallest mass difference Δ'''m''' between two equal magnitude peaks such that the valley between them is a specified fraction of the peak height
 
Smallest mass difference Δ'''m''' between two equal magnitude peaks such that the valley between them is a specified fraction of the peak height
 
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==Controversy==
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IUPAC and ASMS 1991 ([[Price 1991]]) define resolution as m/Δm.
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ASMS 1997 ([[Voyksner 1997]]), Marshall ([[Marshall 2002]]), Sparkman ([[Sparkman 2006]]) define resolution as Δm and resolving power as m/Δm.
  
 
==Gold Book==
 
==Gold Book==
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For a single peak made up of singly charged ions at mass m in a [[Mass Spectrum|mass spectrum]], the resolution may be expressed as m / Δm, where Δm is the width of the peak at a height which is a specified fraction of the maximum peak height. It is recommended that one of three values 50%, 5% or 0.5% should always be used. (Note that for an isolated symmetrical peak recorded with a system which is linear in the range between 5% and 10% levels of the peak, the 5% peak width definition is equivalent to the 10% valley definition. A common standard is the definition of resolution based upon Δm being Full Width of the peak at Half its Maximum (FWHM) height.
 
For a single peak made up of singly charged ions at mass m in a [[Mass Spectrum|mass spectrum]], the resolution may be expressed as m / Δm, where Δm is the width of the peak at a height which is a specified fraction of the maximum peak height. It is recommended that one of three values 50%, 5% or 0.5% should always be used. (Note that for an isolated symmetrical peak recorded with a system which is linear in the range between 5% and 10% levels of the peak, the 5% peak width definition is equivalent to the 10% valley definition. A common standard is the definition of resolution based upon Δm being Full Width of the peak at Half its Maximum (FWHM) height.
 
  
 
== Price 1991 ==
 
== Price 1991 ==

Revision as of 17:21, 8 July 2009