Difference between revisions of "Resolution (mass spectrometry)"
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Smallest mass difference Δ'''m''' between two equal magnitude peaks such that the valley between them is a specified fraction of the peak height | Smallest mass difference Δ'''m''' between two equal magnitude peaks such that the valley between them is a specified fraction of the peak height | ||
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| + | ==Controversy== | ||
| + | IUPAC and ASMS 1991 ([[Price 1991]]) define resolution as m/Δm. | ||
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| + | ASMS 1997 ([[Voyksner 1997]]), Marshall ([[Marshall 2002]]), Sparkman ([[Sparkman 2006]]) define resolution as Δm and resolving power as m/Δm. | ||
==Gold Book== | ==Gold Book== | ||
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For a single peak made up of singly charged ions at mass m in a [[Mass Spectrum|mass spectrum]], the resolution may be expressed as m / Δm, where Δm is the width of the peak at a height which is a specified fraction of the maximum peak height. It is recommended that one of three values 50%, 5% or 0.5% should always be used. (Note that for an isolated symmetrical peak recorded with a system which is linear in the range between 5% and 10% levels of the peak, the 5% peak width definition is equivalent to the 10% valley definition. A common standard is the definition of resolution based upon Δm being Full Width of the peak at Half its Maximum (FWHM) height. | For a single peak made up of singly charged ions at mass m in a [[Mass Spectrum|mass spectrum]], the resolution may be expressed as m / Δm, where Δm is the width of the peak at a height which is a specified fraction of the maximum peak height. It is recommended that one of three values 50%, 5% or 0.5% should always be used. (Note that for an isolated symmetrical peak recorded with a system which is linear in the range between 5% and 10% levels of the peak, the 5% peak width definition is equivalent to the 10% valley definition. A common standard is the definition of resolution based upon Δm being Full Width of the peak at Half its Maximum (FWHM) height. | ||
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== Price 1991 == | == Price 1991 == | ||