Difference between revisions of "Resolution (mass spectrometry)"

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|def='''Synonym:''' [[mass resolution]]
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In a mass spectrum, the observed [[m/z]] value divided by the smallest difference ?(m/z) for two ions that can be separated: (m/z)/ ?(m/z).  
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|def=In a [[mass spectrum]], the observed [[m/z]] value divided by the smallest difference ?(m/z) for two ions that can be separated: (m/z)/?(m/z).
  
:Note 1: The m/z value at which the measurement was made should be reported.  
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:Note 1: The m/z value at which the measurement was made should be reported.
  
:Note 2: The definition and method of measurement of ?(m/z) should be reported. Commonly this is performed using peak width measured at a specified percentage of peak height.  
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:Note 2: The definition and method of measurement of ?(m/z) should be reported. Commonly this is performed using peak width measured at a specified percentage of peak height.
  
:Note 3: Alternatively ?(m/z) is defined as the separation between two adjacent equal magnitude peaks such that the valley between them is a specified fraction of the [[peak]] height, for example as measured by [[peak matching]].
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:Note 3: Alternatively ?(m/z) is defined as the separation between two adjacent equal magnitude peaks such that the valley between them is a specified fraction of the peak height, for example as measured by peak matching.
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|rel=[[Resolving power]]
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|ref={{obgb}}
  
|rel=[[resolution: 10 percent valley definition]], [[resolution: peak width definition]], [[resolving power (mass spectrometry)]].
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G. L. Glish, D. J. Burinsky. J. Am. Soc. Mass Spectrom. 19, 161 (2008).
|ref=
 
{{ob}}
 
 
 
O. D. Sparkman. Mass Spec Desk Reference. Global View Publishing, Pittsburgh (2006)
 
 
 
G. L. Glish, D. J. Burinsky. J. Am. Soc. Mass Spectrom. 19, 161-172 (2008).
 
 
 
A. G. Marshall, C. L. Hendrickson, G. S. Jackson. Mass Spectrom. Rev. 17, 1-35 (1998).
 
 
 
J. Laskin and J. H. Futrell. Mass Spectrom. Rev. 24, 135-167 (2005).
 
  
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J. Laskin, J. H. Futrell. Mass Spectrom. Rev. 24, 135 (2005).
 
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Revision as of 20:57, 7 June 2013

IUPAC RECOMMENDATIONS 2013
Resolution (mass spectrometry)
In a mass spectrum, the observed m/z value divided by the smallest difference ?(m/z) for two ions that can be separated: (m/z)/?(m/z).
Note 1: The m/z value at which the measurement was made should be reported.
Note 2: The definition and method of measurement of ?(m/z) should be reported. Commonly this is performed using peak width measured at a specified percentage of peak height.
Note 3: Alternatively ?(m/z) is defined as the separation between two adjacent equal magnitude peaks such that the valley between them is a specified fraction of the peak height, for example as measured by peak matching.
Related Term(s): Resolving power
Reference(s):

IUPAC. Analytical Division. Compendium of Analytical Nomenclature (the Orange Book). Definitive Rules, 1979. Compiled by J. Inczédy, T. Lengyel, A. M. Ure. Blackwell Scientific Publications, Oxford (1997). On-line corrected version: http://www.iupac.org /publications/analytical compendium (2000).

IUPAC. Compendium of Chemical Terminology, 2nd ed. (the Gold Book). Compiled by A. D. McNaught and A.Wilkinson. Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic, J. Jirat, B. Kosata; updates compiled by A. Jenkins.

G. L. Glish, D. J. Burinsky. J. Am. Soc. Mass Spectrom. 19, 161 (2008).

J. Laskin, J. H. Futrell. Mass Spectrom. Rev. 24, 135 (2005).

From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.

Index of Recommended Terms

 




Other versions

Gold Book

GOLD BOOK DEFINITION

IUPAC. Compendium of Chemical Terminology, 2nd ed. (the Gold Book). Compiled by A. D. McNaught and A.Wilkinson. Blackwell Scientific Publications, Oxford (1997).

Resolution (mass spectrometry)

resolution in mass spectroscopy [sic]

(energy): By analogy with the peak width definition for mass resolution, a peak showing the number of ions as a function of their translational energy should be used to give a value for the energy resolution.

(10 per cent valley definition): Let two peaks of equal height in a mass spectrum at masses m and m - Δm be separated by a valley which at its lowest point is just 10 per cent of the height of either peak. For similar peaks at a mass exceeding m, let the height of the valley at its lowest point be more (by any amount) than ten per cent of either peak height. Then the resolution (10 per cent valley definition) is m/Δm. It is usually a function of m. The ratio m/Δm should be given for a number of values of .

(peak width definition): For a single peak made up of singly charged ions at mass in a mass spectrum, the resolution may be expressed as m/Δm where Δm is the width of the peak at a height which is a specified fraction of the maximum peak height. It is recommended that one of three values 50%, 5% or 0.5% should always be used. For an isolated symmetrical peak recorded with a system which is linear in the range between 5% and 10% levels of the peak, the 5% peak width definition is technically equivalent to the 10% valley definition. A common standard is the definition of resolution based upon being Full Width of the peak at Half its Maximum height, sometimes abbreviated 'FWHM'. This acronym should preferably be defined the first time it is used.

Source: PAC, 1991, 63, 1541 (Recommendations for nomenclature and symbolism for mass spectroscopy (including an appendix of terms used in vacuum technology). (Recommendations 1991)) on page 1554

Orange Book, p. 203

IUPAC Gold Book
Index of Gold Book Terms


Orange Book

ORANGE BOOK DEFINITION

IUPAC. Analytical Division. Compendium of Analytical Nomenclature (the Orange Book). Definitive Rules, 1979.

Resolution (mass spectrometry)

Resolution: 10 Per Cent Valley Definition

Let two peaks of equal height in a mass spectrum at masses m and m - Δm be separated by a valley which at its lowest point is just 10% of the height of either peak. For similar peaks at a mass exceeding m , let the height of the valley at its lowest point be more (by any amount) than 10% of either peak. Then the resolution (10% valley definition) is m / Δm. The ratio m /Δm should be given for a number of values of m.

Resolution: Peak Width Definition

For a single peak made up of singly charged ions at mass m in a mass spectrum, the resolution may be expressed as m / Δm, where Δm is the width of the peak at a height which is a specified fraction of the maximum peak height. It is recommended that one of three values 50%, 5% or 0.5% should always be used. (Note that for an isolated symmetrical peak recorded with a system which is linear in the range between 5% and 10% levels of the peak, the 5% peak width definition is equivalent to the 10% valley definition. A common standard is the definition of resolution based upon Δm being Full Width of the peak at Half its Maximum (FWHM) height.

IUPAC 1997 Orange Book Chapter 12
Index of Orange Book Terms