Selected reaction monitoring: Difference between revisions

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{{Def2|
{{Final|acronym=SRM
Data acquired from specific [[product ion]]s corresponding to ''[[m/z]]'' selected [[precursor ion]]s recorded via two or more stages of mass spectrometry. Selected reaction monitoring can be preformed as tandem mass spectrometry in time or tandem mass spectrometry in space.
|def=Data acquired from one or more specific product [[ion]]s corresponding to [[m/z]] selected [[precursor ion]]s recorded via two or more stages of [[mass spectrometry]].
:''Note 1'': Selected reaction monitoring in [[multiple-stage mass spectrometry]] is known as [[consecutive reaction monitoring]].
:''Note 2'': Selected reaction monitoring applied to multiple product ions from one or more [[precursor ion]]s is known as multiple reaction monitoring.
|rel=[[selected ion monitoring]]
|ref=E. de Hoffmann. J. Mass Spectrom. 31, 129 (1996).


The term [[multiple reaction monitoring]] is deprecated.
}}
}}


== See also ==
{{rm}}
*[[Selected ion monitoring]]


[[Category:Reactions]]
[[Category:Reactions]]
{{DEFAULTSORT:Selected Reaction Monitoring}}
{{DEFAULTSORT:Selected Reaction Monitoring}}
[[Category:Reaction monitoring]]

Latest revision as of 13:02, 31 August 2017

IUPAC RECOMMENDATIONS 2013
Selected reaction monitoring SRM
Data acquired from one or more specific product ions corresponding to m/z selected precursor ions recorded via two or more stages of mass spectrometry.
Note 1: Selected reaction monitoring in multiple-stage mass spectrometry is known as consecutive reaction monitoring.
Note 2: Selected reaction monitoring applied to multiple product ions from one or more precursor ions is known as multiple reaction monitoring.
Related Term(s): selected ion monitoring
Reference(s):

E. de Hoffmann. J. Mass Spectrom. 31, 129 (1996).

From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.

Index of Recommended Terms

 




IUPAC reaction monitoring terms

Term Acronym Definition Diagram Reference
Selected ion monitoring SIM Operation of a mass spectrometer in which the abundances of ions of one or more specific m/z values are recorded rather than the entire mass spectrum.      . Gold Book
Selected reaction monitoring SRM Data acquired from one or more specific product ions corresponding to m/z selected precursor ions recorded via two or more stages of mass spectrometry.
Note 1: Selected reaction monitoring in multiple-stage mass spectrometry is known as consecutive reaction monitoring.
Note 2: Selected reaction monitoring applied to multiple product ions from one or more precursor ions is known as multiple reaction monitoring.
SRM.jpg
de Hoffmann. J. Mass Spectrom. 31, 129 (1996).
Consecutive reaction monitoring CRM Multiple-stage mass spectrometry experiment with three or more stages of m/z separation in which products of sequential fragmentation or bimolecular reactions are selected for detection.
CRM.jpg
Tomer, Guenat, Deterding. Anal. Chem. 60, 2232 (1988).
Multiple reaction monitoring MRM Application of selected reaction monitoring to multiple product ions from one or more precursor ions.
Note: This term should not be confused with consecutive reaction monitoring, which involves the serial application of three or more stages of selected reaction monitoring.
MRM-Single.jpg
Roepstorff, Fohlman. Biomed. Mass Spectrom. 11, 601 (1984).