Top-down proteomics

From MS Terms Wiki
Revision as of 19:21, 8 January 2014 by Kkmurray (talk | contribs)
Jump to navigation Jump to search
Top-down proteomics
Method of protein identification that uses the m/z selection of intact proteins followed by fragmentation and m/z separation in a second stage of mass spectrometry. Mixtures of proteins must first be separated by liquid chromatography or other separation method prior to analysis by mass spectrometry.
Related Term(s):

S. K. Sze, Y. Ge, H. Oh, F. W. McLafferty. Proc. Natl. Acad. Sci. USA 99, 1774 (2002). ( )

N. L. Kelleher. Anal. Chem. 76, 197A (2004). ( )

From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.

Index of Recommended Terms