Category Archives: Fundamentals

Lasers for matrix-assisted laser desorption ionization

K.K. Murray, Lasers for matrix-assisted laser desorption ionization, J. Mass Spectrom., 56 (2021) e4664. https://doi.org/10.1002/jms.4664 Abstract Matrix-assisted laser desorption ionization (MALDI) was introduced 35 years ago and has advanced from a general method for producing intact ions from large biomolecules to wide use in applications ranging from bacteria identification to tissue imaging. MALDI was enabled …

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Sublimation Electrification of Organic Compounds

B. Banstola, K.K. Murray, Sublimation Electrification of Organic Compounds, J. Am. Soc. Mass. Spectrom., 31 (2020) 888-893; doi: 10.1021/jasms.9b00124. Abstract The electrification of crystalline deposits of organic compounds under high vacuum was measured and quantified. A group of compounds that produce multiply charged ions by matrix-assisted ionization were deposited on a metal plate, and the …

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