WP 157
Category Archives: Research Areas
Infrared Laser Ablation Microsampling with a Reflective Objective
Dong, C., Richardson, L.T., Solouki, T., Murray, K.K.: Infrared Laser Ablation Microsampling with a Reflective Objective. J. Am. Soc. Mass. Spectrom. 33, 463-470 (2022). doi: 10.1021/jasms.1c00306 Abstract A Schwarzschild reflective objective with a numerical aperture of 0.3 and working distance of 10 cm was used for laser ablation sampling of tissue for off-line mass spectrometry. …
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Patent: Tip Enhanced Laser Assisted Sample Transfer for Biomolecule Mass Spectrometry
Link Disclosed are various embodiments for transferring molecules from a surface for mass spectrometry and other sample analysis methods, and the like. A laser is focused onto a tip of an atomic force microscope to remove and capture a quantity of molecules from the surface, so they can be transferred to a mass spectrometer or …
ASMS 2021: Matrix Sublimation and Rehydration Chamber for Solvent-based Contrast MALDI Imaging Mass Spectrometry
MP 131
ASMS 2021: Laser Energy Stabilization for Mass Spectrometry Imaging
MP 087
ASMS 2021: Arson Forensic Sampling using Nanoparticle Extraction and Capture
ThP 080
ASMS 2021: Laser Ablation Sampling for Localized Protein Analysis of Mice Exposed to Blast Shock Waves
MP 332
Deep-ultraviolet laser ablation sampling for proteomic analysis of tissue
R.O. Lawal, L.T. Richardson, C. Dong, F. Donnarumma, T. Solouki, K.K. Murray, Deep-ultraviolet laser ablation sampling for proteomic analysis of tissue, Anal. Chim. Acta, 1184 (2021). doi: 10.1016/j.aca.2021.339021 Abstract Deep-ultraviolet laser ablation with a pulsed 193 nm ArF excimer laser was used to remove localized regions from tissue sections from which proteins were extracted for …
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Multimodal Label‐Free Monitoring of Adipogenic Stem Cell Differentiation Using Endogenous Optical Biomarkers
N. Mehta, S. Shaik, A. Prasad, A. Chaichi, S.P. Sahu, Q. Liu, S.M.A. Hasan, E. Sheikh, F. Donnarumma, K.K. Murray, X. Fu, R. Devireddy, M.R. Gartia, Multimodal Label‐Free Monitoring of Adipogenic Stem Cell Differentiation Using Endogenous Optical Biomarkers, Adv. Funct. Mater., (2021) 2103955; doi: 10.1002/adfm.202103955 Abstract Stem cell-based therapies carry significant promise for treating human …
Spatially resolved analysis of Pseudomonas aeruginosa biofilm proteomes measured by laser ablation sample transfer
A.C. Pulukkody, Y.P. Yung, F. Donnarumma, K.K. Murray, R.P. Carlson, L. Hanley, Spatially resolved analysis of Pseudomonas aeruginosa biofilm proteomes measured by laser ablation sample transfer, PLoS One, 16 (2021) e0250911, doi: 10.1371/journal.pone.0250911 Abstract Heterogeneity in the distribution of nutrients and oxygen gradients during biofilm growth gives rise to changes in phenotype. There has been …