Wavelength-Dependent Tip-Enhanced Laser Ablation of Organic Dyes

F. Cao, F. Donnarumma, K.K. Murray, Wavelength-Dependent Tip-Enhanced Laser Ablation of Organic Dyes, Journal of Physical Chemistry C, 124 (2020) 1918-1922; doi: 10.1021/acs.jpcc.9b08081 Abstract The wavelength dependence of atomic force microscope apertureless tip-enhanced laser ablation was studied using a series of organic dyes to assess the effect of surface optical absorption. An optical parametric oscillator […]

Patent: Tip Enhanced Laser Assisted Sample Transfer for Biomolecule Mass Spectrometry

Link Disclosed are various embodiments for transferring molecules from a surface for mass spectrometry and other sample analysis methods, and the like. A laser is focused onto a tip of an atomic force microscope to remove and capture a quantity of molecules from the surface, so they can be transferred to a mass spectrometer or […]

High Resolution Laser Mass Spectrometry Bioimaging

K. K. Murray, , C. A. Seneviratne, and S. Ghorai, “High Resolution Laser Mass Spectrometry Bioimaging” Methods 104 (2016) 118–126; doi:10.1016/j.ymeth.2016.03.002 Mass spectrometry imaging (MSI) was introduced more than five decades ago with secondary ion mass spectrometry (SIMS) and a decade later with laser desorption/ionization (LDI) mass spectrometry (MS). Large biomolecule imaging by matrix-assisted laser […]