IMSC 2018: Infrared Laser Ablation Microsampling Coupled with MALDI Imaging

International Mass Spectrometry Conference, Florence, Italy, August 28, 2018 Louisiana State University: Kermit K. Murray, Fabrizio Donnarumma, Kelin Wang, Carson W. Szot, Chao Dong,Baylor University: Touradj Solouki, Michael E. Pettit Introduction Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) is a powerful method for determining the location of biomolecules in tissue; however, protein identification and […]

IMSC 2018: Combined Infrared and Ultraviolet Ablation Electrospray Ionization Mass Spectrometry

International Mass Spectrometry Conference, Florence, Italy, August 27, 2018 Kermit K. Murray, Remi O. Lawal, and Fabrizio Donnarumma Louisiana State University, Baton Rouge, LA Introduction We are using combined mid-infrared and deep-ultraviolet two-laser ablation coupled with electrospray ionization for ambient mass spectrometry of biomolecules in tissue. The goal is to increase nanoparticle production and improve […]

Small molecule ambient mass spectrometry imaging by infrared laser ablation metastable-induced chemical ionization

Abstract Presented here is a novel ambient ion source termed infrared laser ablation metastable-induced chemical ionization (IR-LAMICI). IR-LAMICI integrates IR laser ablation and direct analysis in real time (DART)-type metastable-induced chemical ionization for open air mass spectrometry (MS) ionization. The ion generation in the IR-LAMICI source is a two step process. First, IR laser pulses […]

ASMS 2007: Laser Desorption Electrospray Ionization

J. Dong, Y. H. Rezenom, and K. K. Murray, โ€œAerosol Desorption Electrospray Ionization,โ€ Presented at the 55th ASMS Conference on Mass Spectrometry, June 4, 2007, Indianapolis, Indiana, Ambient Ionization I, MP 006. American Society for Mass Spectrometry Workshop “Infrared Lasers for MALDI” June 4, 2007 IR Laser + Electrospray Instrument Photos April 16, 2007