Infrared Laser Ablation Microsampling for Mass Spectrometry Imaging (CHE-1709526) is a $0.35M award to Louisiana State University and Baylor University from the National Science Foundation Division of Chemistry to support the development of new techniques for biological imaging. Thank you NSF for 20+ years of support.
This laser has its roots in the STTR grant that I had with OPOTEK starting in 2001 (awarded when I was at Emory but moved immediately to LSU in the first year of Phase I). Our goal was to build an OPO with the capabilities of the Mirage 3000B but in a smaller package.
The left port gives access to the Nd:YAG laser fundamental at 1064 nm and the right port is the 2940 nm mid-IR at about 3 mJ per pulse at 20 Hz. Plenty of energy when focused to efficiently ablate thin films (similar to our wavelength tunable IR Opolette which you can see ablating things here.)
J. Dong, Y. H. Rezenom, and K. K. Murray, “Aerosol Desorption Electrospray Ionization,” Presented at the 55th ASMS Conference on Mass Spectrometry, June 4, 2007, Indianapolis, Indiana, Ambient Ionization I, MP 006.
American Society for Mass Spectrometry Workshop “Infrared Lasers for MALDI” June 4, 2007
IR Laser + Electrospray Instrument Photos April 16, 2007