Patent: Tip Enhanced Laser Assisted Sample Transfer for Biomolecule Mass Spectrometry

Link Disclosed are various embodiments for transferring molecules from a surface for mass spectrometry and other sample analysis methods, and the like. A laser is focused onto a tip of an atomic force microscope to remove and capture a quantity of molecules from the surface, so they can be transferred to a mass spectrometer or […]

Infrared laser ablation and capture of enzymes with conserved activity

Wang, K., Donnarumma, F., Baldone, M. D., & Murray, K. K. Infrared laser ablation and capture of enzymes with conserved activity. Anal Chim Acta, 1027, 41–46 (2018). Abstract Infrared (IR) laser ablation at 3 μm wavelength was used to extract enzymes from tissue and quantitatively determine their activity. Experiments were conducted with trypsin, which was ablated, […]