Infrared laser ablation and capture of enzymes with conserved activity

Wang, K., Donnarumma, F., Baldone, M. D., & Murray, K. K. Infrared laser ablation and capture of enzymes with conserved activity. Anal Chim Acta, 1027, 41–46 (2018). Abstract Infrared (IR) laser ablation at 3 μm wavelength was used to extract enzymes from tissue and quantitatively determine their activity. Experiments were conducted with trypsin, which was ablated, …

High Resolution Laser Mass Spectrometry Bioimaging

K. K. Murray, , C. A. Seneviratne, and S. Ghorai, “High Resolution Laser Mass Spectrometry Bioimaging” Methods 104 (2016) 118–126; doi:10.1016/j.ymeth.2016.03.002 Mass spectrometry imaging (MSI) was introduced more than five decades ago with secondary ion mass spectrometry (SIMS) and a decade later with laser desorption/ionization (LDI) mass spectrometry (MS). Large biomolecule imaging by matrix-assisted laser …