H. Xia, K. Murray, S. Soper, J. Feng, Ultra sensitive affinity chromatography on avidin-functionalized PMMA microchip for low abundant post-translational modified protein enrichment, Biomed. Microdevices, 14 (2012) 67-81; doi: 10.1007/s10544-011-9586-7 Abstract Post-translational modifications (PTM) of proteins play essential roles in cellular physiology and disease. The identification of protein substrates and detection of modification site helps …
Category Archives: Research Areas
Particle Formation in Ambient MALDI Plumes
Infrared Laser Ablation Sample Transfer for MALDI and Electrospray
S.-G. Park, K.K. Murray, “Infrared laser ablation sample transfer for MALDI and electrospray,” J. Am. Soc. Mass Spectrom. 22 (2011) 1352β1362. doi:10.1007/s13361-011-0163-3.
A solid-phase bioreactor with continuous sample deposition for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Proteome analysis of the leukocytes from the American alligator (Alligator mississippiensis) using mass spectrometry
Continuous flow infrared matrixβassisted laser desorption electrospray ionization mass spectrometry
Glossary of terms for separations coupled to mass spectrometry
Wavelength and time-resolved imaging of material ejection in infrared matrix-assisted laser desorption
Development of an efficient on-chip digestion system for protein analysis using MALDI-TOF MS
Microfluidics with MALDI analysis for proteomics
J. Lee, S.A. Soper, K.K. Murray, “Microfluidics with MALDI analysis for proteomics–a review,” Anal. Chim. Acta. 649 (2009) 180β190. doi:10.1016/j.aca.2009.07.037. Abstract Various microfluidic devices have been developed for proteomic analyses and many of these have been designed specifically for mass spectrometry detection. In this review, we present an overview of chip fabrication, microfluidic components, and …
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